Symposium II

A biophysical perspective on degenerative diseases: protein assembly and phase separation

Description

This symposium will show how linking biophysics and neurosciences bring novel insights for the understanding the molecular mechanisms behind many degenerative disorders. The symposium will highlight the use of integrated biophysical approaches to study protein self-assembly and phase separation in degenerative diseases."
Organized as part of the dissemination activities of the Twinning project PhasAGE - Excellence HUB on phase transitions in aging and age-related diseases. This project has received funding from European Union’s Horizon 2020 research and innovation programme under grant agreement No 952334. 

Invited Speakers

Sandra Macedo Ribeiro

Nanobodies as tools to interrogate protein targets in neurodegenerative diseases

IBMC/i3S
University of Porto

Salvador Ventura 

Alfa-helical peptidic scaffolds to target a-synuclein toxic species with nanomolar affinity

IBB
Universitat Autonoma de Barcelona

Ana Melo

HUNTINGTIN EXON 1 BINDING TO LIPID VESICLES: the role of membrane physical properties and the flanking polyQ regions

IBB - IST
University of Lisbon

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